Cephalexin is used to treat bacterial infections in many different parts of the body
Drug-induced liver injury medicines may cause acute or chronic liver damage Jul 29, 2021 · 10
Causality assessment of suspected drug-induced liver injury (DILI) related to antibiotics can be The typical latency period has been 1 to 4 weeks with an abrupt onset of liver injury
, the cerebellum), with substantial blood-brain barrier leakages, promoting the
We call for further improvement in the ‘Applicability’ domain in CPG development, and further researches are needed to strengthen the evidence-based
2174/157488610791698307 Antibiotics are the therapeutic agents most often associated with hepatotoxicity
Tell your doctor if you have kidney disease, liver disease, a stomach or intestinal disorder such as colitis, or diabetes
Keflex Interactions Disease Print Save Keflex Disease Interactions There are 5 disease interactions with Keflex (cephalexin)
Acute liver failure occurs when liver cells are damaged significantly and are no longer able to function
Liver damage
The commonest infection in cirrhotic patients is spontaneous bacterial peritonitis (SBP), followed by urinary tract infection, pneumonia, bacteremia
1–3 Although the frequency of serious antibiotic-induced hepatotoxicity is low compared with the amounts prescribed each year—population-based estimates suggest that it occurs in <5 per 100 000 population 4 —it remains a main reason for antibiotic
mental health side effects Liver function: Cephalexin can cause a decrease in liver function, although this happens only occasionally
Those who have a history of kidney or liver disease, colitis or other stomach disease should not take Keflex
It’s also higher for older adults and people who drink alcohol daily
Nitrofurantoin is an oral antibiotic widely used either short term to treat acute urinary tract infections or long term as chronic prophylaxis against recurrent infections
They also contain: The DILIrank dataset consists of 1,036 FDA-approved drugs that are divided into four classes according to their potential for causing drug-induced liver injury (DILI)
Symptoms can include: nausea; vomiting; pain or tenderness in your abdomen Examples of conditions that could cause problems with Keflex include kidney disease and allergies to (Stevens-Johnson syndrome developed in a 9 month old child given ampicillin [rash] and cephalexin, with subsequent hepatocellular injury [bilirubin 13 mg/dL], resolving with prednisone therapy)
The most common cephalexin (Keflex) side effects are diarrhea, nausea, and stomach pain
Child 12–17 years
LiverTox® provides up-to-date, unbiased and easily accessed information on the diagnosis, cause, frequency, clinical patterns and management of liver injury attributable to prescription and nonprescription medications and selected herbal and dietary supplements
Cephalexin is not expected to be harmful to an unborn baby
an allergy to any drug (especially penicillin); liver or kidney disease; or; intestinal problems, such as They include aspirin (Bayer, Ecotrin), ibuprofen (Advil, Motrin), and naproxen (Aleve, Naprosyn)
Keflex has few serious side effects; however, fluoroquinolones like Cipro can cause Achilles tendon rupture, stroke, arrhythmias, convulsions, liver failure
unpleasant breath odor
Cephalexin is used to treat certain infections caused by bacteria such as pneumonia and other respiratory tract infections; and infections of the bone, skin, ears, , genital, and urinary tract