The organism was stained with an antibody directed toward the cryptococcal capsule
This unique barrier allows cerebral blood vessels to regulate the movement of molecules and ions between the blood and the brain
Two patients (12%) had stable disease in the CNS
The penetration of linezolid into cerebrospinal fluid and brain tissue was studied in 18 patients undergoing a
Several anti-infectives (e
Your blood-brain barrier (BBB) is a protective layer that lines the inner surfaces of the blood vessels inside your brain
All sedating and 'non-sedating' antihistamines cross the blood-brain barrier
They encompass many syndromes, the most
Because daptomycin does not cross the blood-brain barrier in therapeutic concentrations, linezolid was used to treat the brain abscess
There are two key barriers that control the access of endogenous substances and xenobiotics (drugs or toxins) to the CNS
1411 INTRODUCTION: Since the blood-brain barrier (BBB) inhibits drug delivery, transporting pharmacological agents across the BBB is a limiting factor in effective chemotherapy against intracranial neoplasms
It is unclear how insulin is transported across the blood-brain barrier (BBB)
Human immunodeficiency virus type 1 infection increases the in vivo capacity of peripheral monocytes to cross the blood-brain barrier into the brain and the in vivo sensitivity of the blood-brain barrier to disruption by lipopolysaccharide
The major players of the brain innate immune response are microglial cells, the macrophages of brain parenchyma
To date, there is scarce data on the expression of opioid receptors in brain endothelial cells that constitute the blood-brain barrier (BBB)
Electronic databases, such as PubMed, Scopus, and ScienceDirect, were used for search by using “cannabinoids”, “cannabis“, “blood–brain barrier”, “brain delivery”, and “brain disposition” as the main keywords, starting from January 1971 to January 2020
Modeling was based in part on the assumption that only unbound drug is able to cross the BBB
First, the BBB selectively
Previous research has shown that subacute (6 weeks) exposure to formulation herbicides (0
However, a significant hurdle for protein and antibody therapeutics to enter the brain is the blood–brain barrier (BBB)
, glucose, amino acids, peptides, and nucleotides), to selectively cross the blood–brain barrier